Decreased Hormone-Free Intervals and Amenorrhea With Low-Dose Estrogen Combined Hormonal Contraceptives

PhoenixAugust 31, 2025

Panelists discuss how shortened hormone-free intervals (24-4 and 24-2-2 regimens) prevent ovarian reactivation and endometrial proliferation that caused breakthrough bleeding with traditional 21/7 formulations, while addressing how amenorrhea can be viewed as either a desired therapeutic outcome or concerning adverse effect depending on patient preferences.

Contraception Healthcare Reproductive rights United States

By Phoenix